Selected Publications : Biological Physics
(Dr. Sergey Buldyrev)

[Protein Folding and Aggregation] [Alzheimer Research] [Physics of Lungs]
[Statistical Properties of DNA sequences and Molecular Evolution] [Behavior of ecosystems]


Protein Folding and Aggregation
  1. N. Dokholyan, S. V. Buldyrev, H. E. Stanley and E. I. Shakhnovich, "Discrete molecular dynamics studies of the folding of a protein-like model" Folding & Design 3: 577-587 (1998). PDF


  2. N. V. Dokholyan, S. V. Buldyrev, H. E. Stanley, and E. I. Shakhnovich, "Identifying the protein folding nucleus using molecular dynamics." J. Mol. Biol. 296: 1183-1188 (2000) PDF


  3. A. Scala, N. V. Dokholyan, S. V. Buldyrev, H. E. Stanley, and E. I. Shakhnovich, "Thermodynamically important contacts in folding of model proteins" Phys. Rev. E 63: 032901-4 (2001). PDF


  4. J. M. Borreguero, N. V. Dokholyan, S. V. Buldyrev, H. E. Stanley, and E. I. Shakhnovich, "Thermodynamics and folding kinetics analysis of the SH3 domain from Discrete Molecular Dynamics." J. Mol. Biol. 318: 863-876 (2002) PDF


  5. F. Ding, N. V. Dokholyan, S. V. Buldyrev, H. E. Stanley, and E. I. Shakhnovich, "Direct observation of folding transition state ensemble of C-Src SH3 domain in molecular dynamics simulations." Biophys. J. 83: 3525-3532 (2002) PDF


  6. F. Ding, N. V. Dokholyan, S.V. Buldyrev, H. E. Stanley, and E. I. Shakhnovich, "Molecular dynamic simulation of the SH3 domain aggregation suggests a generic amyloidogenesis mechanism." J. Mol. Biol. 324: 851-857 (2002). PDF


  7. F. Ding, J. M. Borreguero, S. V. Buldyrev, { H. E. Stanley}, and N. V. Dokholyan, "Mechanism for the alpha-helix to beta-hairpin Transition," Proteins: Structure, Function, and Genetics 53: 220-228 (2003).PDF


  8. J. M. Borreguero, F. Ding, S. V. Buldyrev, H. E. Stanley, and N. V. Dokholyan, "Multiple Folding Pathways of the SH3 Domain," Biophys. J. 87, 521-533 (2004).


  9. F. Ding, S. V. Buldyrev, and N. V. Dokholyan, "Folding Trp-cage to NMR resolution native structure using a coarse-grained protein model" Biophys. J. 88, 147-155 (2005).PDF


Alzheimer Research
  1. B. T. Hyman, H.L. West, G. W. Rebeck, S. V. Buldyrev, R. N. Mantegna, M. Ukleja, S. Havlin, and H. E. Stanley, "Quantitative analysis of senile plaques in Alzheimer disease: Observation of log-normal size distribution and of differences associated with apolipoprotein E genotype and trisomy 21 (Down syndrome)," Proc. Natl. Acad. Sci. 92: 3586-3590 (1995). PDF


  2. L. Cruz, B. Kutnjac-Urbanc, S. V. Buldyrev, R. Christie, T. Gomez-Isla, S. Havlin, M. McNamara, H. E. Stanley, and B. T. Hyman, "Aggregation and Disaggregation of Senile Plaques in Alzheimer Disease" Proc. National Acad. Sci. 94: 7612-7616 (1997). PDF


  3. B. Urbanc, L. Cruz, S. V. Buldyrev, S. Havlin, H. E. Stanley and B. T. Hyman, "Dynamics of Plaque Formation in Alzheimer Disease" Biophys. J. 76: 1330-1334 (1999). PDF


  4. R. B. Knowles, C. Wyart, S. V. Buldyrev, L. Cruz, B. Urbanc, M.E. Hasselmo, S. Havlin, H. E. Stanley and B. T. Hyman, "Plaque-induced neural network disruption in Alzheimer's disease" Proc. National Acad. Sci. 96: 5274-5279 (1999). PDF


  5. B. Urbanc, L. Cruz, S. V. Buldyrev, S. Havlin, B. T.Hyman, and H. E. Stanley "Dynamic Feedback in an Aggregation-Disaggregation Model" Phys. Rev. E 60: 2120-2126 (1999). PDF


  6. S. V. Buldyrev, L. Cruz, T. Gomez-Isla, S. Havlin, H. E. Stanley, B. Urbanc and B. T. Hyman "Description of Microcolumnar Ensembles in Association Cortex and their Disruption in Alzheimer and Lewy Body Dementias" Proc. National Academy of Sciences 97: 5039-5043 (2000). PDF


  7. B. Urbanc, L. Cruz, F. Ding, D. Sammond, S. Khare, S. V. Buldyrev, H. E. Stanley, and N. V. Dokholyan, "Molecular Dynamics Simulation of Amyloid beta Dimer Formation," Biophys. J. 87: 2310-2321 (2004).


  8. S. Peng, F. Ding, B. Urbanc, S. V. Buldyrev, L. C. Cruz, H. E. Stanley, and N. V. Dokholyan, "Discrete Molecular Dynamics Simulations of Peptide Aggregation" Phys. Rev. E 69: 041908 (2004).


  9. B. Urbanc, L. C. Cruz, Yun S. S. V. Buldyrev, G. Bitan, D. B. Teplow, and H. E. Stanley, "In silico study of amyloid beta-protein folding and oligomerization" Proc. Nat. Acad. Sci. 101: 17345-17350 (2004).


  10. L. C. Cruz, S. V. Buldyrev, S. Y. Peng, D. L. Roe, B. Urbanc, H. E. Stanley, and D. L. Rosene, "A statistically based density map method for identification and quantification of regional differences in microcolumnarity in the monkey brain" J. Neurosci. Methods 141: 321-332 (2005).


  11. J. M. Borreguero, B. Urbanc, N. D. Lazo, S. V. Buldyrev, D. B. Teplow, and H. E. Stanley, "Folding events in the 21-30 region of amyloid-beta-protein (A beta) studied in silico" Proc. Nat. Acad. Sci. 102: 6015-6020 (2005).


Physics of Lungs
  1. A.-L. Barabasi, S. V. Buldyrev, H. E. Stanley, and B. Suki, "Avalanches in the Lung: A Statistical Mechanical Approach," Phys.Rev. Lett. 76: 2192-2195 (1996). PDF


  2. M. K. Sujeer, S. V. Buldyrev, S. Zapperi, J. Andrade, H. E. Stanley, and B. Suki, "Volume Distributions of Avalanches in Lung Inflation: A Statistical Mechanical Approach" Phys. Rev. E 56: 3385-3394 (1997). PDF


  3. A. M. Alencar, Z. Hantos, F. Hantos, F. Petak, J. Tolnai, T. Asztalos, S. Zapperi, J. S. Andrade, S. V. Buldyrev, H. E. Stanley, and B. Suki, "Scaling Behavior in Crackle Sound during Lung Inflation" Phys. Rev E 60: 4659-4663 (1999). PDF


  4. M. P. Almeida, J. S. Andrade Jr., S. V. Buldyrev, F. S. A. Cavalcante, H. E. Stanley, and B. Suki, "Fluid Flow through Ramified Structures" Phys. Rev. E 60: 5486-5494 (1999). PDF


  5. A. M. Alencar, S. V. Buldyrev, A. Majumdar, H. E. Stanley, and B. Suki, "Avalanche Dynamics of Crackle Sound in the Lung" Phys. Rev. Lett. 87: 088101-4 (2001). PDF


  6. A. Majumdar, A. M. Alencar, S. V. Buldyrev, Z. Hantos, H. E. Stanley and B. Suki, "Characterization of the Branching Structure of the Lung from Macroscopic Pressure-Volume Measurements" Phys. Rev. Letters 87: 058102-4 (2001). PDF


  7. A. M. Alencar, S. Arold, S. V. Buldyrev, A. Majumdar, D. Stamenovic, H. E. Stanley, and B. Suki, "Dynamic Instabilities in the Inflating Lung," Nature 417: 809--811 (2002). PDF


  8. A. Majumdar, A. M. Alencar, S. V. Buldyrev, Z. Hantos, H. E. Stanley,and B. Suki, "Fluid transport in branched structures with temporary closures: A model for quasistatic lung inflation" Phys. Rev. E 67: 031912 (2003). PDF


  9. A. M. Alencar, S. V. Buldyrev, A. Majumdar, H. E. Stanley,and B. Suki, "Perimeter Growth of a Branched Structure: Application to Crackle Sounds in the Lung" Phys. Rev. E 68: 11909 (2003). PDF


  10. B. Suki, A. M. Alencar, U. Frey, P. Ch. Ivanov, S. V. Buldyrev, A. Majumdar, H. E. Stanley, C. A. Dawson, G. S. Krenz, and M. Mishima, "Fluctuations, Noise, and Scaling in the Cardio-Pulmonary System," Fluctuations and Noise Letters 3, R1-R25 (2003).


Statistical Properties of DNA sequences and Molecular Evolution
  1. C. K. Peng, S. V. Buldyrev, A. Goldberger, S. Havlin, F. Sciortino, M. Simons and H. E. Stanley, "Long-Range Correlations in Nucleotide Sequences," Nature 356: 168--171 (1992).


  2. S. V. Buldyrev, A. L. Goldberger, S. Havlin, C.-K. Peng, M. Simons, and H. E. Stanley, "Generalized L\'evy Walk Model for DNA Nucleotide Sequences," Phys. Rev. E 47: 4514-4523 (1993). PDF


  3. S. V. Buldyrev, A. L. Goldberger, S. Havlin, C.-K. Peng, H. E. Stanley and M. Simons, "Fractal Landscapes and Molecular Evolution: Modeling the Myosin Heavy Chain Gene Family" Biophys. J. 65: 2675-2681 (1993).


  4. S. V. Buldyrev, A. Goldberger, S. Havlin, C.-K. Peng, F. Sciortino, M. Simons and H. E. Stanley, "On Long-Range Power Law Correlations in DNA", Phys. Rev. Lett. 71: 1776 (1993). PDF


  5. C. K. Peng, S. V. Buldyrev, A. L. Goldberger, S. Havlin, M. Simons, and H. E. Stanley, "Finite Size Effects on Long-Range Correlations: Implications for Analyzing DNA Sequences," Phys. Rev. E 47:, 3730-3733 (1993). PDF


  6. C. K. Peng, S. V. Buldyrev, S. Havlin, M. Simons, H. E. Stanley and A. L. Goldberger, "Mosaic Organization of DNA Sequences," Phys. Rev. E 49: 1685-1689 (1994). PDF


  7. S. M. Ossadnik, S. V. Buldyrev, A. L. Goldberger, S. Havlin, R.N. Mantegna, C.-K. Peng, M. Simons, and H. E. Stanley, "Correlation Approach to Identify Coding Regions in DNA Sequences" Biophys. J. 67: 64-70 (1994).


  8. S. V. Buldyrev, A. L. Goldberger, S. Havlin, R. N. Mantegna, M. E. Matsa, C.-K. Peng, M. Simons, and H. E. Stanley, "Long-Range Correlation Properties of Coding and Noncoding DNA Sequences: GenBank Analysis," Phys. Rev. E 51: 5084-5091 (1995). PDF


  9. R. N. Mantegna, S. V. Buldyrev, A. L. Goldberger, S. Havlin, C.-K. Peng, M. Simons, and H. E. Stanley, "Systematic Analysis of Coding and Noncoding DNA Sequences Using Methods of Statistical Linguistics," Phys. Rev. E 52: 2939-2950 (1995). PDF


  10. G. M. Viswanathan, S. V. Buldyrev, S. Havlin, and H. E. Stanley, "Quantification of DNA Patchiness using Correlation Measures," Biophys. J. 72: 866-875 (1997).


  11. N. V. Dokholyan, S. V. Buldyrev, S. Havlin, and H. E. Stanley, "Distribution of Base Pair Repeats in Coding and Noncoding DNA Sequences" Phys. Rev. Lett. 79: 5182-5185 (1997). PDF


  12. S. V. Buldyrev, N.V. Dokholyan, A.L. Goldberger, S. Havlin, C.-K. Peng, H.E. Stanley and G.M. Viswanathan "Analysis of DNA Sequences Using Methods of Statistical Physics," Physica A 249: 430-438 (1998). PDF


  13. N. Dokholyan, S. V. Buldyrev, S. Havlin, and H. E. Stanley, "Model of unequal chromosomal crossing over" Physica A 249: 594-599 (1998). PDF


  14. R. H. R. Stanley, N. V. Dokholyan, S. V. Buldyrev, S. Havlin, and H. E. Stanley, "Clumping of Identical Oligonucleotides in Coding and Noncoding DNA Sequences," J. Biomol. Structure and Dynamics 17: 79-87 PDF


  15. S. V. Buldyrev, N. V. Dokholyan, S. Havlin, H. E. Stanley, and R. H. R. Stanley, "Expansion of Tandem Repeats and Oligomer Clustering in Coding and Noncoding DNA Sequences" Physica A 273: 19-32 (1999). PDF


  16. N. Dokholyan, S. V. Buldyrev, S. Havlin, and H. E. Stanley, "Distributions of Dimeric Tandem Repeats in Non-coding and Coding DNA Sequences," J. Theor. Biol. 202: 273-282 (2000). PDF


  17. I. Grosse, H. Herzel, S. V. Buldyrev, and H. E. Stanley, "Species Independence of Mutual Information in Coding and Noncoding DNA," Phys. Rev. E 61: 5624-5629 (2000). PDF


Behavior of ecosystems
  1. B. Jovanovic, S. V. Buldyrev, S. Havlin, H. E. Stanley, "Punctuated Equilibrium and `History Dependent' Percolation," Phys. Rev. E 50: R2403-R2406 (1994). PDF


  2. G. M. Viswanathan, V. Afanasyev, S. V. Buldyrev, E. J. Murphy, P. A. Prince, and H. E. Stanley, "Levy Flight Search Patterns of Wandering Albatrosses" Nature 381: 413-415 (1996).


  3. H. E. Stanley, V. Afanasyev, L. A. N. Amaral, S. V. Buldyrev, A. L. Goldberger, S. Havlin, H. Leschhorn, P. Maass, R. N. Mantegna, C.-K. Peng, P. A. Prince, M. A. Salinger, M. H. R. Stanley, and G. M. Viswanathan, "Anomalous Fluctuations in the Dynamics of Complex Systems: From DNA and Physiology to Econophysics" Physica A 224: 302-321 (1996). PDF


  4. G. M. Viswanathan, S. V. Buldyrev, S. Havlin, M. G. da Luz, E. Raposo, and H. E. Stanley, "Optimizing the Success of Random Searches" Nature 401: 911-914 (1999). PDF


  5. G. M. Viswanathan, S. V. Buldyrev, E. Garger, V. A. Kashpur, L. S. Lucena, A. Shlyakhter, J.Tschiersch, and H. E. Stanley, "Log-Normal Behavior of 137Cs Concentration Fluctuations Around Chernobyl" Phys. Rev. E 62: 4389-4392 (2000). PDF


  6. S. V. Buldyrev, S. Havlin, A. Ya. Kazakov, M. G. E. da Luz, E. P. Raposo, H. E. Stanley, and G. M. Viswanathan, "Average Time Spent by Levy Flights and Walks on an Interval with Absorbing Boundaries" Phys. Rev. E 64: 041108-11 (2001). PDF


  7. S. V. Buldyrev, M. Gitterman, S. Havlin, A. Ya. Kazakov, M. G. E. da Luz, E. P. Raposo, H. E. Stanley, and G. M. Viswanathan, "Properties of Levy fights on an interval with absorbing boundaries" Physica A 302: 148-161 (2001). PDF


  8. T. H. Keitt, L. A. N. Amaral, S. V. Buldyrev, and H. E. Stanley, "Scaling in the Growth of Geogrpahically Subdivided Populations: Scale-Invariant Patterns from a Continent-Wide Biological Survey" Phil. Trans. Royal Soc. B Biological Sciences 357: 627-633 (2002).


  9. E. Raposo, S. V. Buldyrev, M. G. da Luz, M. C. Santos, H. E. Stanley, G. M. Viswanathan, "Dynamical robustness of Levy search strategies" Phys. Rev. Lett.91: 240601-4 (2003). PDF